Two sample MR report
IAH1_Alveolar Macrophages against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 16 | -0.0361363 | 0.2370965 | 0.8810369 |
| Weighted median | 16 | 0.0687422 | 0.0198832 | 0.0005456 |
| Inverse variance weighted | 16 | 0.0638781 | 0.0149759 | 0.0000200 |
| Simple mode | 16 | 0.0858295 | 0.0285159 | 0.0087939 |
| Weighted mode | 16 | 0.0584330 | 0.0241912 | 0.0289363 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 4.595731 | 14 | 0.9906820 |
| Inverse variance weighted | 4.774384 | 15 | 0.9938704 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0602261 | 0.1424882 | 0.6789532 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0002514 | 0 | TRUE | 0.1322159 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
